Our ability to determine the validity of such assertions and the exact role of opioids in the treatment of chronic pain will benefit from further study. Opioid effectiveness, addiction, and depression in chronic pain. N2 - Opioids are a viable treatment for chronic pain, but their use requires individualization, specified treatment goals, and patient education.
AB - Opioids are a viable treatment for chronic pain, but their use requires individualization, specified treatment goals, and patient education. School of Medicine. Abstract Opioids are a viable treatment for chronic pain, but their use requires individualization, specified treatment goals, and patient education. Fingerprint Chronic Pain. Opioid Analgesics.
Addictive Behavior. Narcotic Antagonists. Calcium Channel Blockers. Patient Education.
Advances in Psychosomatic Medicine , 25 , In: Advances in Psychosomatic Medicine , Vol. Advances in Psychosomatic Medicine.
J Psychopharmacol ; 43 - Endogenous opioids: biology and function. Annu Rev Neurosci ;7: - Pattinson KT. Opioids and the control of respiration. Br J Anaesth ; - Classical conditioning and pain: conditioned analgesia and hyperalgesia. Acta Psychol Amst ; 10 - Analgesics as reinforcers with chronic pain: evidence from operant studies. Neurosci Lett ; Pt A: 60 - Abuse risks and routes of administration of different prescription opioid compounds and formulations.
Harm Reduct J ;8: 29 - Department of Health and Human Services. Guidance for industry: abuse-deterrent opioids: evaluation and labeling. Mastropietro DJ, Omidian H. Abuse-deterrent formulations: part 2: commercial products and proprietary technologies. Expert Opin Pharmacother ; - Drugs ; - Cellular and synaptic adaptations mediating opioid dependence.
Physiol Rev ; - Age-dependent opioid escalation in chronic pain patients. Anesth Analg ; - Comparative study of the effectiveness of slow-release morphine and methadone for opioid maintenance therapy. Addiction ; - Kornetsky C, Bain G. Morphine: single-dose tolerance. Science ; - Ethanol reversal of tolerance to the respiratory depressant effects of morphine. Neuropsychopharmacology ; - Differential development of acute tolerance to analgesia, respiratory depression, gastrointestinal transit and hormone release in a morphine infusion model.
Life Sci ; - Major opioids and chronic opioid therapy. Philadelphia: Mosby Elsevier, Wax P, Ruha A. Withdrawal syndromes: opioid withdrawal. Targeting opioid-induced hyperalgesia in clinical treatment: neurobiological considerations. CNS Drugs ; - Front Pharmacol ;5: - Clinical interpretation of opioid tolerance versus opioid-induced hyperalgesia. J Opioid Manag ; - A comprehensive review of opioid-induced hyperalgesia. Pain Physician ; - Methadone related deaths compared to all prescription related deaths.
Forensic Sci Int ; - Paulozzi LJ. Prescription drug overdoses: a review. J Safety Res ; - Risk of adverse health outcomes with increasing duration and regularity of opioid therapy. J Am Board Fam Med ; - The role of opioid prescription in incident opioid abuse and dependence among individuals with chronic noncancer pain: the role of opioid prescription. Clin J Pain ; - Prescription opioid duration of action and the risk of unintentional overdose among patients receiving opioid therapy.
Opioids and the management of chronic severe pain in the elderly: consensus statement of an International Expert Panel with focus on the six clinically most often used World Health Organization Step III opioids buprenorphine, fentanyl, hydromorphone, methadone, morphine, oxycodone. Pain Pract ;8: - Opioid therapy and sleep disorders: risks and mitigation strategies. Pain Med ; Suppl 1 : S22 - 6. Preventing iatrogenic overdose: a review of in-emergency department opioid-related adverse drug events and medication errors.
Ann Emerg Med ; - Risk factors for drug dependence among out-patients on opioid therapy in a large US health-care system. Alcohol involvement in opioid pain reliever and benzodiazepine drug abuse-related emergency department visits and drug-related deaths — United States, Epidemiology of emergency department visits for opioid overdose: a population-based study.
Mayo Clin Proc ; - Developmental neurocircuitry of motivation in adolescence: a critical period of addiction vulnerability.
Am J Psychiatry ; - Callop N, Cassel DK. Snoring and sleep disordered breathing. Sleep medicine. Analgesics in patients with hepatic impairment: pharmacology and clinical implications. Verbeeck RK. Pharmacokinetics and dosage adjustment in patients with hepatic dysfunction. Eur J Clin Pharmacol ; - Mercadante S, Arcuri E. Opioids and renal function.
J Pain ;5: 2 - Christie MJ. Cellular neuroadaptations to chronic opioids: tolerance, withdrawal and addiction.
Br J Pharmacol ; - The neural basis of addiction: a pathology of motivation and choice. Volkow ND, Morales M.
The brain on drugs: from reward to addiction. Cell ; - Uhl GR, Drgo T. Genetic contributions to individual differences in vulnerability to addiction and abilities to quit. Drug abuse and addiction in medical illness: causes, consequences and treatment. New York: Springer, 95 - Implications of genome wide association studies for addiction: are our a priori assumptions all wrong?
Pharmacol Ther ; - Genetics of opioid dependence: a review of the genetic contribution to opioid dependence. Curr Psychiatry Rev ; - Co-occurrence of abuse of different drugs in men: the role of drug-specific and shared vulnerabilities. Arch Gen Psychiatry ; - Genetic and environmental influences on posttraumatic stress disorder, alcohol and drug dependence in twin pairs.
Drug Alcohol Depend ; 95 - Public policy statement on rapid and ultra rapid opioid detoxification. Mortality from overdose among injecting drug users recently released from prison: database linkage study. BMJ ; - Overdose after detoxification: a prospective study. Drug Alcohol Depend ; - Common elements in guidelines for prescribing opioids for chronic pain. Atlanta: Centers for Disease Control and Prevention, Motives, diversion and routes of administration associated with nonmedical use of prescription opioids.
Addict Behav ; - Clinical guidelines for the use of chronic opioid therapy in chronic noncancer pain.